Home Tools
Log in
Cart

Search Result

Search Results for " protac bcl-xl degrader-2 "

6

Compounds

Cat No. Product Name Synonyms Targets
T74138 PROTAC Bcl-xL degrader-2
PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.
T39910 Desmorpholinyl Navitoclax-NH-Me Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me BCL
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
T40135 PZ703b
PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.
T73957 PROTAC Bcl-xL degrader-1
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits to...
T39909 XZ739 XZ739
XZ739 is a Cereblon-dependent PROTAC BCL-XL degrader, targeting a member of the Bcl-2 family, with a DC50 value of 2.5 nM in MOLT-4 cells after 16 hours of treatment. Additionally, XZ739 elicits cell death via caspase-me...
T73826 PZ703b hydrochloride
PZ703b hydrochloride, a Bcl-xl PROTAC degrader, effectively induces apoptosis and curbs the proliferation of cancer cells. It is primarily utilized in the study of bladder cancer [1] [2].
TargetMol